商业

Dimension INX筹集了1200万美元的资金:旨在提高新一代再生疗法的商业化

Biomaterials platform companyDimension Inx宣布已关闭了A票A系列赛的$ 1200万。

Prime Movers实验室(PML)领导了这一巡回演出,与返回投资者合作KdT VenturesRevolution’s Rise of the Rest Seed Fund(ROTR)。SOLAS BIOVENTURES,,,,Portal Innovation Ventures, 和校友冒险are among the new investors in this round. The funds will be employed to accelerate the development of functional organ regeneration therapeutics and to broaden the company’s manufacturing capabilities. The funds will be used to assist in the commercial release of the firm’s first product, CMFlex, in the near future.

Dimension INX还显示,CMFLEX是FDA批准的第一个3D打印的修复式骨移植产品,已从美国食品药品监督管理局(FDA)获得了510(k)的清除率。CMFLEX是一种用于口服和上颌种族适应症的现成多功能陶瓷,可增强临床医生的工作流程并减少手术病例时间,同时还可以恢复健康的骨骼。

Prime Movers Lab Venture合作伙伴Amy Kruse博士说:“ Dimension INX代表了我们认为将改变其行业并重塑其物理世界的突破科学类型。”谁将加入公司董事会。“我们很高兴能在下一阶段的增长和开发阶段,并将其变革性产品推向市场时,我们很高兴支持Dimension Inx。”

“FDA clearance is a major milestone for our platform, and validates the work we’ve put into developing our product over the past two years,” said CEO of Dimension Inx, Caralynn Nowinski Collens, M.D. “CMFlex is a product that represents our unique approach to restoring functionality in the body: it’s a dynamic collaboration between biology, material composition, microstructure, and macro architecture. We’re excited by the interest we’ve already received from surgeons who recognize the importance of a ready-to-use solution that is easy to handle and accelerates healing to improve patient outcomes.”

A representative example of a small sheet of Tissue PaperTM derived from ovarian tissue, highlighting its unique micro- and nano-porosity and texture. Image via Dimension Inx.
A representative example of a small sheet of Tissue PaperTM derived from ovarian tissue, highlighting its unique micro- and nano-porosity and texture. Image via Dimension Inx.

Dimension Inx’s industrial 3D printing portfolio

Previously, a team ofCarnegie Mellon University(CMU)和University of Connecticut(UCONN)研究人员3D印刷的新型磷酸钙石墨烯(CAPG)支架,这些支架将来可以用于骨骼恢复应用。Dimension Inx’s Direct Ink Writing (DIW) 3D printing method团队用来用大量分数打印其CAPG材料的多孔概念,以允许墨水内“明显高”的石墨含量(约90%)。这允许细胞进入整骨主链以及磷酸盐和钙离子的持续释放,表明操作石墨烯含量,而不是生物启动粘合剂,主导了宿主对基质的响应。

“We pride ourselves in catalyzing a step function change to unlock the full potential of regenerative therapeutics to cure complex disease, and we’re grateful to do so with the support of our investors,” added Dr. Collens. “Our approach has always focused on the entire tissue microenvironment. If we provide the right blueprint, we make it possible to recruit the body’s natural strengths and accelerate the repair, regeneration, and ultimately, restoration of critical body function.”

Furthermore, theUS Department of Defense(DoD) granted Dimension Inx $240,000 in funding建立能够恢复气管损伤的再生医疗系统。该项目使用该公司的专利生物材料平台生产可植入的零件,以模仿气管微环境,并将它们与新型水凝胶合并,以帮助重塑为典型的功能性气管组织。

Dimension Inx has raised over $3 million to fund the development of its 3D bioprinting technology. Image via Dimension Inx.
Dimension Inx has raised over $3 million to fund the development of its 3D bioprinting technology. Image via Dimension Inx.

在增材制造业中进行的系列资金回合

Previously, San Francisco-based on-demand manufacturing service provider虚构筹集了1亿美元E系列资金。This round of funding increased the firm’s total capital raised to about $192 million.激活资本LED Fictiv的E系列赛,并从成熟的机构投资者参与Accel,,,,比尔盖茨,,,,G2 Venture Partners, 和Standard InvestmentsAngeleno集团,,,,十字溪, 和Westly Groupjoined as new investors.

在其他地方,瑞士碳纤维3D印刷专家9T Labs筹集了1700万美元Series A funding,,,,which it used to commercialize its Red Series Additive Fusion Solution platform. The platform, which combines 3D printing and compression molding, is intended for the creation of advanced carbon fiber-reinforced thermoplastic composite parts in quantities varying from 100 to over 100,000 parts per year. With the support of industrial 3D printer manufacturerStratasys,,,,as well as other key investors, 9T Labs sought to fully commercialize the platform to produce components for end-use applications in the aerospace, automotive, medical, industrial, and consumer goods industries.

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什么工程挑战在未来十年中,是否需要在增材制造业中解决?

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特征图像显示了源自卵巢组织的一小部分组织纸的代表性示例,突出了其独特的微孔和质地。图像通过Dimension INX。

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