医疗和牙科

方面生物系统3D bioprinting kidney tissue with Maastricht University

3D生物打印技术公司方面生物系统宣布与马斯特里赫特大学(UM) in the Netherlands. The focus of their project is to develop viable kidney tissue for medical testing.

将其RX1 Bioprointer放在洛伦佐教授莫罗尼的实验室,方面将与技术风格的再生医学研究所(Merln)在UM。

Faction Biosystems的总裁兼首席执行官Tamer Mohamed解释说:“经常发现挽救生命,但繁重的透析治疗的患者在等待供应量严格限制的供体器官。组织工程师认识到他们工作的潜力减轻了这一问题,但是肾脏组织很复杂且极具挑战性。”

“By combining the deep expertise at MERLN with our microfluidic 3D printing technology, we are increasing our capacity to tackle these kidney-related challenges head-on.”

Aspect's bioprinter in action. Photo via Aspect Biosystems.
方面的3D生物生产商行动。通过方面生物系统的照片。

创建人体组织的所有方面

Biosystems是一家成立于2013年的私有生物技术公司。该公司的目的是按需创建人体组织,并且在与UM的最新合作中,它正在进一步努力实现这一目标。

Mohamed explains that “At Aspect, we are committed to collaborating with leading research groups in tissue engineering and regenerative medicine to realize the broad applicability of our technology,”

The Aspect RX1 Bioprinter facilitates the fabrication of 3D tissues using the Lab-on-a-Printer™ platform, Aspect’s core technology powered by microfluidics. The Lab-on-a-Printer™ platform has printheads containing microscopic channels for the redirection of multiple fluids and inks at a time. With this capability, the technology enables the layering of multiple cell types to create 3D tissue structures.

The MERLN Institute

Merln将研究与培训生物医学工程领域的跨学科科学家相结合。它专门制造用于细胞组织再生的设备。

The institute has been working on kidney bioprinting for 3 years, and has now developed new bioinks to help maintain and regenerate the health of kidney cells during the bioprinting process.

MERLN uses extrusion, droplet-on-demand and microfluidics to develop tissue implants and organ models, and has already developed constructs for long bone defects. Dr. Carlos Mota, head of bioprinting research and assistant professor at MERLN, will be leading the project into developing kidney tissue using 3D bioprinting technology.

3D bioprinter at Maastricht University. Photo via Carlos Mota.
3D bioprinter at Maastricht University. Photo via Carlos Mota.

The institute will be working with Aspect to 3D bioprint kidney tissue at The Moroni Lab, a research group specializing in biofabrication technologies. The group was founded in 2009 at the University of Twente, the Netherlands, and is a part of the MERLN institute at UM.

“This is an exciting opportunity,” says Prof. Moroni and Dr. Mota. “We already took our first steps in kidney tissue models and we are particularly excited to apply our expertise with Aspect’s platform technology and join forces with their innovative team, which we expect will accelerate our findings and impact in this space.”

方面可以选择根据研究结果进一步开发和商业化产品。

与生物系统在同一领域运营的其他公司包括Organovo, that already has itsExVive™市场上的人类肾脏材料,胶结植物, which providescollagen biomaterials

方面的应用3D生物打印给人留下了深刻的印象吗?在即将到来的2019 3D印刷行业奖。

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特色图片显示Aspect的3D BioProinter在行动中。通过方面生物系统的照片。