生物材料开发人员Jellatech在开发其3D可打印的基于细胞的胶原蛋白生物Ink方面，宣布了一个新的里程碑。
经过两年的发展，该公司成功地设计了由自己专有的细胞系制成的全长，三螺旋和功能性的胶原蛋白。
“This is a major milestone for us and I am beyond proud and excited that we are already here,” said Stephanie Michelsen, CEO of Jellatech. “Being able to see our clean cell-based collagen with the naked eye – it brings happy tears.”
3D printing with collagen
胶原蛋白是在结缔组织，皮肤，肌腱，骨骼和软骨中发现的哺乳动物中最独特，最丰富的蛋白质之一。它为组织提供结构支持，并在组织修复，免疫反应和细胞迁移等细胞过程中起重要作用。
胶原蛋白的财产已导致它在许多行业中广泛使用，例如生物医学，健康，个人护理和美容，材料以及食品和饮料领域。但是，由于仅在动物和植物中发现蛋白质，许多公司正在寻找其他新颖和可持续的来源。
关于3D打印应用程序，到目前为止，基于胶原蛋白的生物互联组织再生的潜力, to create癌症幸存者的乳房植入物和生产联合重建的人造软骨, among other things.
基于细胞的胶原蛋白生物学也有助于3D打印的Alt-Meat的增长市场，由Meatech之类的人用,重新定义肉, and others
Jellatechbelieves it now has the answer to sustainable cell-based collagen production with the development of its new bioink, which it says could lead to further novel applications in the future.
Jellatech’s collagen bioink
根据Jellatech的说法，基于细胞的胶原蛋白比植物胶原蛋白具有许多优势。例如，由于无法提供与动物衍生的胶原蛋白相同的功能，因此对植物性胶原蛋白生物学的应用受到限制。
“Collagen formation is a complex process that requires specialized machinery found only in mammalian cells,” said Christopher Gilchrist, Senior Scientist at Jellatech. “We’re working to harness the innate ability of these cells to produce collagen that is bio-identical to native collagen and do it in a sustainable and animal-free way.”
Avoiding animal slaughter completely, the company’s collagen production process works by taking small skin samples of animal cells lines which are then cultured in bioreactors in its lab. The collagen protein is extracted, purified, and filtered out through a series of process to form a collagen bioink that is bioidentical to the collagen extracted from animals.
Jellatechrefers to its process as “100% guilt-free” due to bypassing animal slaughter completely, and sees it as a sustainable alternative source of collagen.
Jellatech科学负责人Rob Schutte补充说：“我们很高兴看到我们的细胞来源的胶原蛋白似乎是源自动物的胶原蛋白的生物。”“因此，从生物医学到化妆品再到食品和饮料，我们都有广泛的激动人心的应用。”
Convinced her firm’s cell-based technology is a step ahead of other collagen production technologies currently contributing to the global $8.4 billion market, Michelsen added: “It is becoming more and more evident that we need to change many of our existing practices and the way that we sustain our planet.
“This achievement just shows that we have a way and now we have laid to stepping stones for a sustainable future of protein production.”
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特色图片显示Jellatech的纯白色胶原蛋白形式。通过Jellatech的照片。
