South Korean pharmaceutical company香港Inno.n宣布的计划使用人工3D印刷皮肤来测试新的自身免疫性和皮肤疾病药物。
Working with 3D bioprinting firmT＆R Biofab, HK inno.N plans to fabricate a series of tissues with precisely-tailored characteristics. Leveraging the 3D printed flesh, the companies will conduct in-depth research into the effectiveness of different skin disease medications. If the evaluations are successful, the additive tissues could be utilized as a future replacement for animal testing in the medical and cosmetics industries.
“我们不仅将使用人造皮肤来验证药物对皮肤疾病的功效，而且我们还将在两家公司之间进行积极的研究，以便将其用于研究健康功能性食品和化妆品材料，” Koh Dong-HK Inno.N研究所负责人Hyun对韩文时代。
T＆R Biofab的3D生物打印技术
Based in the Korean city of Seoul, T&R Biofab was founded in 2013 by a team from波哈科学技术大学（Postech）。研究人员利用其联合专家从大学获得了其3D生物打印技术的专利，并成立了一家风险投资公司，以将其添加剂商业化。
七年后，该公司现在进行了广泛的组织再生研究，并设计了用于移植的医疗设备，并在骨科，整形外科和牙科中应用。T＆R还正在开发其专利的脱纤维生物墨水，据报道，它可以创建细胞外膜（ECMS）和组织特异性皮肤，肝脏，骨骼或软骨组织的生物打印。
2019年4月，T＆R Bioofabpatented its 3D bioprinting technologyfor creating artificial skin. The firm’s additive manufacturing technique involves fabricating both the dermal and epidermal layers of skin cells using a porous 3D structure. Later that year, T&R advanced its methodology further, developing a新的多嘴嘴生物打印系统，允许它在较短的时间内创建复杂的单元结构。
As T&R’s technology has progressed, the pharmaceutical firm has entered into a number of partnerships with the aim of expanding its applications. Working with fellow biotechnology businessSCM生活科学，T＆R正在研究和开发一系列3D打印的单元格产品，包括新的细胞疗法制剂。
最近在2020年5月，该公司由韩国卫生与战争部领导干细胞和再生医学商业化项目。该计划据报道，预算为8.25亿韩国赢了，在暴露于实验药物的情况下，正在研究干细胞衍生的人心脏细胞的反应。现在，与HK Inno签订了协议。N，T＆R Bioofab将部署其生物打印专业知识，以测试皮肤病药物的影响。
香港Inno之间的交易。N和T＆R Bioofab
为了立即开始研究项目，香港Inno。n，以前称为CJ Healthcare，于2020年8月25日与T＆R Bioofab签署了一份谅解备忘录（MOU）。该协议介绍了一项围绕“使用3D生物涂纸人工皮肤评估药物和功能材料的评估”的联合研发计划。
During the joint-study, HK Inno.N plans to deploy T&R Biofab’s 3D bioprinting technology to fabricate structures that function in a similar way to actual skin. T&R’s flesh-based models reportedly make it possible to measure skin elasticity, aging index, and protein expression amongst other features. 3D printing also allows the fabricated skin to be customized in a way that meets HK inno.N’s precise needs and enables the firm to find more efficient ways of testing the experimental drugs.
总体而言，通过部署T＆R的生物打印专业知识HK Inno。N的目的是为患有自身免疫性疾病的患者开发新的皮肤疗法。T＆R Bioofab首席执行官Yoon Won-Soo表示，这些公司的合作可以进一步扩展到涉及健康功能食品和化妆品材料的研究中。
“This collaboration with HK Inno.N will be a meaningful step toward full commercialization of our 3D printed skin and related drug screening technologies,” said Yoon Won-soo in a statement. “We will complete innovative products that can be effectively used in industrial sites such as cosmetics and new drug development.”
继续研究3D生物打印组织
Developing optimized bio-inks for 3D printing tissue scaffolds is one of the hottest research topics in additive manufacturing right now, with numerous researchers developing their own formulations.
来自新泽西州的工程师罗格斯大学已经设计了new customizable bio-ink for 3D printing scaffolds。由透明质酸和聚乙烯乙二醇组成，一旦与其他墨水混合，可以定制凝胶，以制造一系列人体组织。
南非的研究人员威特沃特斯兰大学, assessed thesafety and efficiency of existing 3D printed bio-inks。科学家发现，为了使多细胞生物打印的大规模采用，需要开发一种新型的生物墨水。
来自苏黎世有创建了通用纳米载体墨水（UNI）平台这可以使新的生物功能墨水的生产。通过将聚合物掺入其Uni配方中，苏黎世团队能够通过辅助交联制造具有增强强度的稳定脚手架。
Nominations for the2020 3D印刷行业奖仍然是开放的,让我们知道谁是领导印第安纳州ustry now.
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特色图片显示了T＆R Biofab的3D生物打印技术。图像通过T＆R生物托车。
