Researchers atCarnegie Mellon Universityhave developed an open-source, low-cost 3D bioprinter. They have published a paper inHardwareXwith the complete instructions for the installation of a syringe-based large volume extruder (LVE) on a desktop FDM 3D printer.
人类是住允许用户打印人工sues at a high resolution and scale. It is designed to print a range of materials, including biopolymers, hydrogels, pastes and epoxies.
Adam Feinberg, one of the authors of the paper and a Biomedical Engineering Associate Professor at Carnegie Mellon, said “The LVE 3D bioprinter allows us to print much larger tissue scaffolds, at the scale of an entire human heart, with high quality.”
Democratising technology, making 3D bioprinting more accessible
Feinberg says that the LVE can be installed for less than $500. The modifications were applied to aPrintrBot Simple 3D printer, though the authors say the LVE should be compatible with many desktop FDM 3D printers.
大多数商业3D生物发电机的价格在10,000-200,000美元之间。市场上最便宜的3D生物生产商是Allevi 1, at $4,995. Feinberg claims that the LVE is “at least on par with many [3D bioprinters] that cost far more money”, though he did not name any specific 3D bioprinters for comparison.
Theoretically compatible with any open-source FDM 3D printer
Kira Pusch, a recent graduate from Materials Science and Engineering at Carnegie Mellon said that “What we’ve created is a large volume syringe pump extruder that works with almost any open source fused deposition modelling (FDM) printer. This means that it’s an inexpensive and relatively easy adaptation for people who use 3D printers.”
卡内基·梅隆（Carnegie Mellon）的费恩伯格（Feinberg）实验室的目标是生产更多的开源生物医学研究，以加速生物医学创新的速度。Feinberg说：“这实际上是关于使技术民主化并试图将其融入更多人的手中。”
We envision this as being the first of many technologies that we push into the open source environment to drive the field forward. It’s something we really believe in.
Researchers at theUniversity of Manchesterare makinghuman cell models using 3D bioprintingin hopes of finding the cause of Alzheimer’s disease. Oxford, UK, based 3D bioprinting companyOxSyBiohas raised$14 million in series A financing, with the long term goal of having 3D bioprinters produce tissue transplants.
一篇题为“桌面3D打印机的大容量注射器泵送器”的论文，其中详细介绍了文章中列出的3D Bioprinter，该详细信息在Hardwarex Journal中在线发布。它由基拉·普施（Kira Pusch），托马斯·J.Hinton（Thomas J.Hinton）和亚当·费恩伯格（Adam Feinberg）合着。
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Featured image shows the open-source 3D models of all the 3D printed components required for the LVE. Image via Kira Pusch, Thomas J.Hinton, Adam Feinberg.
